Biological control is a natural method to control the size of animal, microorganism or plant populations. Biological control is based on the knowledge of inharmonious (negative) ecological interactions between species. Using such knowledge a parasite, competitor or predator species is introduced in an ecosystem in order to attain reduction of the population of another species with which it has inharmonious ecological interaction. The biological control presents the advantage of substituting the use of pesticides and other toxic chemical products in the control of plagues and diseases. It however should be employed with caution under serious previous study to avoid harmful ecological disequilibrium. A kind of biological control of some species can be done by the introduction of previously sterilized males, that do not generate offspring.